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Furthermore, it's been reported that blasts obtained from patients with relapsed FLT3 ITD good leukemia may perhaps show increased sensitivities towards tyrosine kinase inhibitors on account of a increased ad diction to FLT3 read more...

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One particular sample, taken from a bone marrow aspirate of a patient with de novo AML, was identified to harbor a FLT3 ITD mutation from the juxtamembrane domain of the gene. IC50 was in